FDA Recall of Benzoyl Peroxide Acne Products Raises Safety Concerns

March 21, 2025

Keeping You Updated on Important FDA News

In March 2025, the U.S. Food and Drug Administration (FDA) announced a major recall of over-the-counter acne treatments after several tested positive for benzene, a known human carcinogen. Among the brands affected is the widely used La Roche-Posay Effaclar Duo Dual Action Acne Treatment, triggering alarm among dermatologists and consumers.


Which Acne Products Were Recalled?

The recall impacts approximately 95 acne treatment products, including:

  • La Roche-Posay Effaclar Duo Dual Action Acne Treatment

  • Proactiv Emergency Blemish Relief Cream Benzoyl Peroxide 5%

  • Proactiv Skin Smoothing Exfoliator

  • Walgreens Acne Control Cleanser

  • ZAPZYT Acne Treatment Gel

These products contain benzoyl peroxide, a standard ingredient in acne treatment. While long used safely, testing revealed the presence of benzene in select batches, prompting the FDA to act.


Why Is Benzene in Skincare a Problem?

Benzene is a carcinogen. It’s not supposed to be in skincare products, especially not in daily-use treatments applied directly to the skin. The FDA confirmed that, although the risk is considered low, prolonged exposure to elevated levels is concerning, especially for topical products.


How to Check If Your Product Is Affected

Look for:

  • Product name and brand

  • Lot number (usually printed on the container or outer packaging)

  • Expiration date

All La Roche-Posay Effaclar Duo products expiring through October 2025 are part of the recall. Consumers are advised to stop using recalled products and contact manufacturers for return and refund procedures.

What Steps Should You Take?

The FDA recommends the following actions:

  • Stop use immediately

  • Follow return instructions from the manufacturer

  • Consult your healthcare provider if any adverse effects occur

  • Retain proof of purchase and packaging for returns

Retailers must remove all affected products from shelves by April 2025, but individuals should act immediately.


What Caused the Contamination?

Although benzene is not an ingredient in these formulations, it may have been introduced during manufacturing or formed during degradation. The FDA continues to investigate, and its findings may reshape how benzoyl peroxide products are produced and tested.

la-roche-posay-recall-benzene-levels-chart


Benzoyl Peroxide Is Not the Enemy

Not all products containing benzoyl peroxide are affected. The ingredient remains FDA-approved when properly formulated and monitored. Consumers should not avoid it entirely but should instead choose brands with stringent quality controls and verified testing protocols.


Safe Alternatives for Acne Management

Prescription Options
  • Tazorac® (Tazarotene) Cream or Gel – Retinoid for acne and photoaging

  • Aczone® (Dapsone) Gel 7.5% – A non-antibiotic option effective for inflammatory acne

  • SkinMedica® by Allergan® Aesthetics – Includes physician-developed products for acne-prone skin

Over-the-Counter Options
  • Salicylic acid-based treatments – Gently exfoliate and clear pores

  • Adapalene gel 0.1% – Formerly prescription-only, now available OTC

  • Sulfur spot treatments – Useful for reducing inflammation with minimal irritation


Industry Implications of the Recall

This recall will likely lead to:

  • Tighter testing regulations for benzoyl peroxide products

  • Greater transparency from skincare brands

  • Increased demand for pharmaceutical-grade options from trusted companies like Allergan® Aesthetics

Dermatologists may see a surge in patients looking for prescription alternatives and guidance on safe skincare selections.


How to Choose Acne Treatments Wisely

When replacing your current acne treatment:

  • Check for FDA compliance

  • Investigate manufacturing and testing standards

  • Speak with a licensed medical professional

  • Opt for clinically tested and dermatologist-developed brands


FAQ: Acne Product Recall

Which benzoyl peroxide acne treatments were recalled?

Around 95 products, including La Roche-Posay Effaclar Duo, Proactiv, and Walgreens formulations.

What is benzene and why is it unsafe?

Benzene is a chemical classified as a carcinogen. It’s not supposed to be in skincare products, but contamination may occur during manufacturing or storage.

Should I be worried if I’ve used these products?

The FDA reports the risk is low, but advises stopping use and following return procedures.

Are any benzoyl peroxide products safe?

Yes. Not all products tested positive for benzene. Choose items from companies with strict quality controls and published testing results.

Is the recall still ongoing?

Yes, and the FDA continues to evaluate and update the list of affected products.


Final Thoughts

The recent acne product recall reveals how even widely trusted skincare items can face quality issues. Fortunately, several safe, dermatologist-developed alternatives remain available. Look for brands with rigorous testing, FDA oversight, and clinical validation—like those from Allergan® Aesthetics.

Staying informed is the best way to protect your skin and health. When in doubt, consult your healthcare provider for recommendations tailored to your needs.

Contact Pipeline Medical today, for more information.


This article is for informational purposes only and does not constitute medical advice. Please consult with a healthcare professional before beginning any new skincare regimen.