BOTOX® Cosmetic (onabotulinumtoxinA) is an FDA-approved prescription medicine that is injected into muscles and used to temporarily improve the look of moderate to severe forehead lines, crow’s feet, and frown lines between the eyebrows in adults.
BOTOX® Cosmetic works by blocking neuromuscular transmission by binding to acceptor sites on motor nerve terminals, entering the nerve terminals, and inhibiting the release of acetylcholine. This inhibition occurs as the neurotoxin cleaves SNAP-25, a protein integral to the successful docking and release of acetylcholine from vesicles situated within nerve endings.
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